General
Preferred name
PYRVINIUM PAMOATE
Synonyms
PYRVINIUM ()
Pyrvinium embonate ()
Vanquin ()
Povan ()
Poquil ()
Pyrvinium (as embonate) ()
NSC-223622 ()
Vanquil ()
Pyrvinium (pamoate) ()
P&D ID
PD051663
CAS
3546-41-6
Tags
available
drug
Drug Status
approved
Max Phase
4.0
Drug indication
pancreatic ductal adenocarcinoma
First approval
1982
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
49
DESCRIPTION
Pyrvinium pamoate (Pyrvinium embonate) is an old anthelminthic medicine for the treatment of enterobiasis , which re-attracts attention as an anti-cancer drug due to its inhibition of Wnt/??-catenin pathway in some types of cancer.
DESCRIPTION
Pyrvinium is an anthelmintic agent used for the treatment of pinworm infestations.
(Enamine Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
2
Compound Sets
9
AdooQ Bioactive Compound Library
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Enamine Bioactive Compounds
Enamine BioReference Compounds
MedChem Express Bioactive Compound Library
Prestwick Chemical Library
Selleckchem Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
1150.54
Hydrogen Bond Acceptors
10
Hydrogen Bond Donors
2
Rotatable Bonds
12
Ring Count
12
Aromatic Ring Count
12
cLogP
12.34
TPSA
144.82
Fraction CSP3
0.15
Chiral centers
0.0
Largest ring
6.0
QED
0.12
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Wnt
Parasite
Pathway
Stem Cell/Wnt
Source data
