General
Preferred name
florbetapir
Synonyms
FLORBETAPIR F 18 ()
Florbetapir F-18 ()
Florbetapir (18f) ()
Av45 f-18 ()
18f-av45 ()
Florbetapir, f-18 ()
18F-AV-45 ()
Amyvid ()
(18F)AV-45 ()
AV-45 F-18 ()
Florbetapir(18-f) ()
AV-45 ()
P&D ID
PD051659
CAS
956103-76-7
Tags
drug
available
Approved by
FDA
First approval
2012
Drug indication
Diagnostic imaging
Cognitive impairment
Drug Status
approved
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Florbetapir F18 is a molecular imaging agent (diagnostic radiopharmaceutical) that binds to β-amyloid aggregates in Alzheimer's brains.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
ChEMBL Approved Drugs
ChEMBL Drugs
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
NCATS Inxight Approved Drugs
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
43
Molecular Weight
360.18
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
12
Ring Count
2
Aromatic Ring Count
2
cLogP
3.68
TPSA
52.61
Fraction CSP3
0.35
Chiral centers
0.0
Largest ring
6.0
QED
0.59
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
