General
Preferred name
CX614
Synonyms
CX 614 ()
P&D ID
PD051552
CAS
191744-13-5
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
CX614 is a positive allosteric modulator of the AMPA receptor with respect to AMPA.
(GtoPdb)
DESCRIPTION
Selective TRPA1 activator
(Tocris Bioactive Compound Library)
DESCRIPTION
CX 614 has been found to be an AMPA modulator and has also been found to be an ampakine drug facilitating activation of glutamatergic AMPA receptors.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
BOC Sciences Bioactive Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
17
Molecular Weight
247.08
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
0
Rotatable Bonds
0
Ring Count
4
Aromatic Ring Count
1
cLogP
1.41
TPSA
48.0
Fraction CSP3
0.46
Chiral centers
1.0
Largest ring
6.0
QED
0.7
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
AMPA Receptors
MOA
Modulator
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
iGluR
Source data
