General
Preferred name
NF546
Synonyms
NF 546 ()
P&D ID
PD051477
CAS
1006028-37-0
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION D2 and D3 agonist (Tocris Bioactive Compound Library)
Compound Sets
7
Concise Guide to Pharmacology 2017/18
4046
Concise Guide to Pharmacology 2019/20
4046
Concise Guide to Pharmacology 2021/22
4046
Concise Guide to Pharmacology 2023/24
4046
DrugMAP
DMPZB31
Guide to Pharmacology
4046
Tocris Bioactive Compound Library
3892
External IDs
13
Properties
(calculated by RDKit )
Molecular Weight
1180.13
Hydrogen Bond Acceptors
13
Hydrogen Bond Donors
10
Rotatable Bonds
22
Ring Count
6
Aromatic Ring Count
6
cLogP
8.1
TPSA
343.65
Fraction CSP3
0.13
Chiral centers
4.0
Largest ring
6.0
QED
0.02
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Primary Target
Purinergic (P2Y) Receptors
MOA
Agonist
Source data