General
Preferred name
megestrol
Synonyms
Megace ()
P&D ID
PD051472
CAS
3562-63-8
Tags
available
drug
Drug indication
Breast cancer
Drug Status
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Megestrol (commonly administered as the acetate ester: PubChem CID 11683) is a synthetic derivative of the female sex hormone progesterone. It has anti-estrogenic and antineoplastic activity. (GtoPdb)
Compound Sets
7
Drug Repurposing Hub
DrugMAP
DMDH9KX
DrugMAP Approved Drugs
DMDH9KX
Guide to Pharmacology
9128
MedChem Express Bioactive Compound Library
HY-B1834
NCATS Inxight Approved Drugs
EA6LD1M70M
Selleckchem Bioactive Compound Library
megestrol
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
342.22
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
4
Aromatic Ring Count
0
cLogP
4.0
TPSA
54.37
Fraction CSP3
0.73
Chiral centers
6.0
Largest ring
6.0
QED
0.78
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Indication
breast cancer
MOA
Progesterone receptor agonist
Therapeutic Class
Anticancer Agents
Pathway
Metabolic Enzyme/Protease
Target
Drug Metabolite
Estrogen/progestogen Receptor
Source data