General
Preferred name
ACRIFLAVINE
Synonyms
Acriflavinium chloride 3,6-Acridinediamine mix ()
P&D ID
PD051410
CAS
65589-70-0
50922-89-9
8048-52-0
51555-26-1
68518-47-8
Tags
available
drug candidate
Drug indication
Human immunodeficiency virus infection
Drug Status
experimental
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Acriflavine (Acriflavinium chloride 3,6-Acridinediamine mix) is a papain-like protease (PL(pro)) inhibitor, a fluorescent dye for labeling high molecular weight RNAs, has antimicrobial and anticancer activity, inhibits SARS-CoV-2 and other β-coronaviruses, and can be used for research on leukemia. be used to study leukemia.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
4
DrugBank
DrugMAP
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
468.18
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
4
Rotatable Bonds
0
Ring Count
6
Aromatic Ring Count
6
cLogP
1.54
TPSA
120.85
Fraction CSP3
0.04
Chiral centers
0.0
Largest ring
6.0
QED
0.15
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Antibacterial
SARS-CoV-2
HIF
Pathway
Microbiology/virology
Source data
