General
Preferred name
BW723C86
Synonyms
BW 723C86 hydrochloride ()
BW-723C86 ()
BW 723C86 ()
BW-723C86 hydrochloride ()
P&D ID
PD051344
CAS
160521-72-2
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 5-HT2B agonist (Tocriscreen Plus)
DESCRIPTION 5-HT2B agonist (Tocriscreen Total)
DESCRIPTION BW 723C86 hydrochloride is a selective 5-HT2B receptor agonist used for the treatment of certain CNS disorders, such as epilepsy, migraine and feeding disorders. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
1
Compound Sets
14
BOC Sciences Bioactive Compounds
bw-723c86-hydrochloride-cas-160521-72-2-363726
Cayman Chemical Bioactives
70090
Concise Guide to Pharmacology 2017/18
161
Concise Guide to Pharmacology 2019/20
161
Concise Guide to Pharmacology 2021/22
161
Concise Guide to Pharmacology 2023/24
161
DrugMAP
DME15JU
Guide to Pharmacology
161
Ki Database
BW-723C86
MedChem Express Bioactive Compound Library
HY-101369
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Tocriscreen Plus
1059
Tocriscreen Total
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
286.11
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
3
Aromatic Ring Count
3
cLogP
3.7
TPSA
51.04
Fraction CSP3
0.25
Chiral centers
1.0
Largest ring
6.0
QED
0.75
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
7-TM Receptors
Member status
virtual
MOA
HTR2B agonist
Pathway
GPCR/G protein
Neuronal Signaling
Target
5-HT Receptor
Source data