General
Preferred name
hydroxyproline
Synonyms
L-Hydroxyproline ()
(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid ()
trans-4-Hydroxy-L-proline ()
trans-4-hydroxy-proline ()
trans-4-hydroxy L-Proline ()
trans-4-hydroxy L-Proline-d3 ()
P&D ID
PD051320
CAS
147028-80-6
51-35-4
1356016-86-8
Tags
available
drug
Approved by
FDA
Drug Status
approved
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Compound Sets
13
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugCentral
DrugCentral Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
External IDs
51
Properties
(calculated by RDKit )
Molecular Weight
131.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
0
cLogP
-1.21
TPSA
69.56
Fraction CSP3
0.8
Chiral centers
2.0
Largest ring
5.0
QED
0.42
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
MOA
Endogenous Metabolite
Pathway
Metabolic Enzyme/Protease
Source data