General
Preferred name
hydroxyproline
Synonyms
L-Hydroxyproline ()
trans-4-Hydroxy-L-proline ()
Trans-4-Hydroxyproline ()
L-Hydroxyprolin ()
(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid ()
trans-4-hydroxy-proline ()
trans-4-hydroxy L-Proline ()
P&D ID
PD051320
CAS
51-35-4
147028-80-6
Tags
natural product
drug
available
Approved by
FDA
Drug Status
experimental
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Compound Sets
14
Cayman Chemical Bioactives
26061
Concise Guide to Pharmacology 2017/18
4704
Concise Guide to Pharmacology 2019/20
4704
Concise Guide to Pharmacology 2021/22
4704
Concise Guide to Pharmacology 2023/24
4704
Drug Repurposing Hub
DrugBank
DB08847
DrugCentral
4272
DrugCentral Approved Drugs
4272
Guide to Pharmacology
4704
MedChem Express Bioactive Compound Library
HY-40135
ReFrame library
Selleckchem Bioactive Compound Library
l-hydroxyproline
TargetMol Bioactive Compound Library
T2A2476
External IDs
44
Properties
(calculated by RDKit )
Molecular Weight
131.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
3
Rotatable Bonds
1
Ring Count
1
Aromatic Ring Count
0
cLogP
-1.21
TPSA
69.56
Fraction CSP3
0.8
Chiral centers
2.0
Largest ring
5.0
QED
0.42
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolism
Metabolic Enzyme/Protease
Target
Endogenous Metabolite
Source data