General
Preferred name
FONDAPARINUX
Synonyms
Fondaparinux (sodium) ()
Fondaparin sodium ()
SR-90107A ()
Natural heparin pentasaccharide Sodium ()
Arixtra ()
FONDAPARINUX SODIUM ()
Natural heparin pentasaccharide Sodium, Fondaparin sodium, SR-90107A ()
Fondaparinux Sodium (Org 31540) ()
Fondaparinux (sodium salt) ()
ORG31540 FREE ACID ()
SR-901107A ()
SR 901107A ()
ORG-31540 FREE ACID ()
Fondaparinux sodique ()
Fondaparinux sodico ()
Quixidar ()
ORG 31540 ()
Fondaparinux sodium for assay ()
Fondaparinux sodium identification ()
SR 90107A DECASODIUM SALT ()
ORG-31540 ()
SR 90107A ()
SR-90107A DECASODIUM SALT ()
IC-851589 ()
P&D ID
PD051070
CAS
104993-28-4
114870-03-0
Tags
available
drug
Approved by
FDA
First approval
2001
Drug indication
Atrial fibrillation
Venous thromboembolism
Venous thrombosis
Drug Status
approved
withdrawn
investigational
Max Phase
4.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Synthetic pentasaccharide Factor Xa inhibitor (via ATIII binding). The ChEMBL and PubChem links given here are without the sodium ions contained in the INN structure of this compound. Database entries include the sodium salt (e.g. PubChem CID 636380).
(GtoPdb)
DESCRIPTION
Fondaparinux sodium (SR-90107A) is an antithrombin-dependent factor Xa inhibitor with antithrombotic activity.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
23
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
66
Molecular Weight
1506.95
Hydrogen Bond Acceptors
39
Hydrogen Bond Donors
19
Rotatable Bonds
30
Ring Count
5
Aromatic Ring Count
0
cLogP
-13.75
TPSA
805.48
Fraction CSP3
0.94
Chiral centers
25.0
Largest ring
6.0
QED
0.03
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Factor Xa
F10, SERPINC1
Pathway
Metabolic Enzyme/Protease
Metabolism
Indication
deep vein thrombosis (DVT)
MOA
coagulation factor inhibitor
ATC
B01AX05
Biosynthetic Origin
Carbohydrate (Aminoglycoside)
Therapeutic Indication
Anticoagulant
Therapeutic Class
Cardiovascular
Anticoagulants
Source data
