General
Preferred name
FONDAPARINUX
Synonyms
Fondaparinux (sodium) ()
Fondaparin sodium ()
SR-90107A ()
Natural heparin pentasaccharide Sodium ()
Arixtra ()
FONDAPARINUX SODIUM ()
Fondaparinux Sodium (Org 31540) ()
Natural heparin pentasaccharide Sodium, Fondaparin sodium, SR-90107A ()
SR 90107A ()
ORG-31540 ()
Fondaparinux sodium for assay ()
Fondaparinux sodium identification ()
ORG 31540 ()
Quixidar ()
IC-851589 ()
Fondaparinux (sodium salt) ()
P&D ID
PD051070
CAS
114870-03-0
104993-28-4
Tags
available
drug
Approved by
FDA
First approval
2001
Drug Status
investigational
approved
withdrawn
Drug indication
Venous thrombosis
Max Phase
Phase 4
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Synthetic pentasaccharide Factor Xa inhibitor (via ATIII binding). The ChEMBL and PubChem links given here are without the sodium ions contained in the INN structure of this compound. Database entries include the sodium salt (e.g. PubChem CID 636380).
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
23
Cayman Chemical Bioactives
ChEMBL Approved Drugs
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugBank Approved Drugs
DrugCentral
DrugCentral Approved Drugs
DrugMAP
DrugMAP Approved Drugs
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
Other bioactive compounds
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
61
Molecular Weight
1506.95
Hydrogen Bond Acceptors
39
Hydrogen Bond Donors
19
Rotatable Bonds
30
Ring Count
5
Aromatic Ring Count
0
cLogP
-13.75
TPSA
805.48
Fraction CSP3
0.94
Chiral centers
25.0
Largest ring
6.0
QED
0.03
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Factor Xa
F10, SERPINC1
Pathway
Metabolic Enzyme/Protease
Metabolism
Indication
deep vein thrombosis (DVT)
MOA
coagulation factor inhibitor
ATC
B01AX05
Biosynthetic Origin
Carbohydrate (Aminoglycoside)
Therapeutic Indication
Anticoagulant
Therapeutic Class
Cardiovascular
Anticoagulants
Source data
