General
Preferred name
PD051007
Synonyms
5-Carboxamidotryptamine maleate ()
5-carboxamidotryptamine ()
5-CT ()
[3H]5-CT ()
[3H]5-CT ()
P&D ID
PD051007
CAS
74885-72-6
74885-09-9
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
5-HT7 Serotonin receptor agonist
(LOPAC library)
DESCRIPTION
5-HT1 agonist. Also has high affinity for 5-ht5a and 5-HT7
(Tocriscreen Total)
DESCRIPTION
Selective 5-HT2 antagonist; also 3C-like proteinase inhibitor
(Tocris Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
15
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugMatrix
Ki Database
LOPAC library
Mcule NIBR MoA Box Subset
Novartis Chemogenetic Library (NIBR MoA Box)
Tocris Bioactive Compound Library
Tocriscreen Total
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
34
Molecular Weight
203.11
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
3
Rotatable Bonds
3
Ring Count
2
Aromatic Ring Count
2
cLogP
0.77
TPSA
84.9
Fraction CSP3
0.18
Chiral centers
0.0
Largest ring
6.0
QED
0.69
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
5-HT7
Primary Target
Non-selective 5-HT1
MOA
Agonist
serotonin receptor agonist
Member status
member
Target
HTR1A, HTR1B, HTR1D, HTR1E, HTR1F, HTR2A, HTR2B, HTR2C, HTR5A, HTR6, HTR7
Source data
