General
Preferred name
NFPS
Synonyms
[3H]NFPS ()
Alx-5407 ()
ALX 5407 hydrochloride ()
P&D ID
PD051000
CAS
405225-21-0
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Non-selective inhibitor of dopamine and noradrenalin transporters
(Tocris Bioactive Compound Library)
DESCRIPTION
NFPS is a non-transportable GlyT1 inhibitor.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
BOC Sciences Bioactive Compounds
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
CZ-OPENSCREEN Bioactive Library
DrugMAP
EUbOPEN Chemogenomics Library
ReFrame library
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
20
Molecular Weight
393.17
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
9
Ring Count
3
Aromatic Ring Count
3
cLogP
5.02
TPSA
49.77
Fraction CSP3
0.21
Chiral centers
1.0
Largest ring
6.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Glycine Transporters
MOA
Inhibitor
Recommended Cell Concentration
None
Source data
