General
Preferred name
DPDPE
Synonyms
DPDPE TFA ()
DPDPE (TFA) ()
DPDPE TFA (88373-73-3 free base) ()
DPDPE (trifluoroacetate salt) ()
P&D ID
PD050964
CAS
88373-73-3
88381-29-7
172888-59-4
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
experimental
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION DPDPE TFA is selective δ-opioid receptor agonist peptide. Inhibits electrically stimulated contraction of mouse vas deferens in vitro (EC50 = 5.2 nM), and is antinociceptive in vivo. (TargetMol Bioactive Compound Library)
Cell lines
0
Organisms
2
Compound Sets
7
Cayman Chemical Bioactives
23184
DrugBank
DB08861
DrugMAP
DMIRSNA
EUbOPEN Chemogenomics Library
EUB0000938
Guide to Pharmacology
1608
MedChem Express Bioactive Compound Library
HY-P1334
HY-P1334A
TargetMol Bioactive Compound Library
TP2036L
External IDs
26
Properties
(calculated by RDKit )
Molecular Weight
645.23
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
7
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
2
cLogP
1.11
TPSA
199.95
Fraction CSP3
0.43
Chiral centers
4.0
Largest ring
14.0
QED
0.21
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
Opioid Receptor
δ-opioid receptor
Pathway
GPCR/G protein
Neuronal Signaling
Endocrinology/Hormones
Neuroscience
Recommended Cell Concentration
100 nM
Source data