General
Preferred name
clopidogrel (active metabolite)
Synonyms
P&D ID
PD050946
Tags
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION The structure shown here is of the active metabolite of , a pro-drug which is activated in the liver by cytochrome P450 enzymes.
DESCRIPTION The structure shown here is of the active metabolite of , a pro-drug which is activated via 2-oxo-clopidogrel (PubChem CID 56848893) by cytochrome P450 enzymes in the liver. This compound is an irreversible antagonist of the platelet P2Y12 receptor . The antagonist effect is stereoselective for the S-enantiomer shown here, whereas the R-enantiomer is almost inactive. (GtoPdb)
Compound Sets
1
Guide to Pharmacology
1772
External IDs
9
Properties
(calculated by RDKit )
Molecular Weight
355.06
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
2
Rotatable Bonds
4
Ring Count
2
Aromatic Ring Count
1
cLogP
2.57
TPSA
66.84
Fraction CSP3
0.38
Chiral centers
2.0
Largest ring
6.0
QED
0.49
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Source data