General
Preferred name
SURINABANT
Synonyms
SR-147778 ()
Sr147778 ()
P&D ID
PD050930
CAS
288104-79-0
Tags
available
drug candidate
Drug indication
smoking cessation
Obesity
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Surinabant is a selective, orally active cannabinoid CB1 receptor antagonist , investigated for potential use as an aid to smoking cessation. CB1 receptor antagonists may have clinical potential in other addictions (e.g. alcoholism ) or conditions such as attention deficit hyperactivity disorder (ADHD) .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
ChEMBL Drugs
DrugBank
DrugMAP
Guide to Pharmacology
LSP-MoA library (Laboratory of Systems Pharmacology)
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Molecular Weight
520.04
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
5
Ring Count
4
Aromatic Ring Count
3
cLogP
6.3
TPSA
50.16
Fraction CSP3
0.3
Chiral centers
0.0
Largest ring
6.0
QED
0.43
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
