General
Preferred name
L-739750
Synonyms
L-739,750 ()
P&D ID
PD050882
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
The discovery of L-739,750 is described in . L-739,750 is a peptidomimetic farnesyltransferase inhibitor (FTI). Experimentally the compound is administered as a methyl ester prodrug (L-739,749) .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
11
Molecular Weight
517.23
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
5
Rotatable Bonds
17
Ring Count
1
Aromatic Ring Count
1
cLogP
0.88
TPSA
147.82
Fraction CSP3
0.65
Chiral centers
5.0
Largest ring
6.0
QED
0.19
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
