General
Preferred name
AZD-7268
Synonyms
AZD7268 ()
Azd 7268 ()
AZ12488024 ()
AZ-12488024 ()
P&D ID
PD050862
CAS
1018988-00-5
Tags
available
drug candidate
Drug indication
Major depressive disorder
Anxiety disorder
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
AZD7268 is a potent, selective and reversible CNS‐penetrating and orally bioavailable δ-opioid receptor agonist.
This compound was in the AstraZeneca/MRC repurposing list from 2011. (GtoPdb)
This compound was in the AstraZeneca/MRC repurposing list from 2011. (GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
ChEMBL Drugs
DrugBank
DrugMAP
Guide to Pharmacology
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
15
Molecular Weight
498.21
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
5
Aromatic Ring Count
4
cLogP
4.85
TPSA
69.56
Fraction CSP3
0.28
Chiral centers
0.0
Largest ring
6.0
QED
0.39
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
