General
Preferred name
UCL1684
Synonyms
UCL 1684 ()
P&D ID
PD050784
CAS
199934-16-2
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Benzodiazepine inverse agonist; selective for alpha5-containing GABAA receptors (Tocris Bioactive Compound Library)
Compound Sets
8
Concise Guide to Pharmacology 2017/18
2320
Concise Guide to Pharmacology 2019/20
2320
Concise Guide to Pharmacology 2021/22
2320
Concise Guide to Pharmacology 2023/24
2320
DrugMAP
DMZNJFU
Guide to Pharmacology
2320
Tocris Bioactive Compound Library
1310
ZINC Tool Compounds
ZINC000003960761
External IDs
10
Properties
(calculated by RDKit )
Molecular Weight
494.25
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
9
Aromatic Ring Count
6
cLogP
6.2
TPSA
31.82
Fraction CSP3
0.12
Chiral centers
2.0
Largest ring
21.0
QED
0.25
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Related compounds
Custom attributes
(extracted from source data)
Primary Target
Calcium-Activated Potassium (KCa) Channels
MOA
Blocker
Source data