General
Preferred name
EPACADOSTAT
Synonyms
P&D ID
PD050731
Tags
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Epacadostat (INCB024360) is an orally bioavailable, potent, small molecule inhibitor of indoleamine-2,3-dioxygenase 1 (IDO1) , with therapeutic potential in immunodeficiency-associated abnormalities, including cancer.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
1
Guide to Pharmacology
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
8
Molecular Weight
436.99
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
5
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
1
cLogP
0.17
TPSA
159.3
Fraction CSP3
0.18
Chiral centers
0.0
Largest ring
6.0
QED
0.3
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data
