General
Preferred name
DZNep
Synonyms
P&D ID
PD050724
Tags
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION DZNep was originally identified as an inhibitor of S-adenosylhomocysteine (AdoHcy) hydrolase . Subsequently DZNep has been reported to inhibit EZH2 histone methyltransferase activity . (GtoPdb)
Compound Sets
5
Concise Guide to Pharmacology 2017/18
8392
Concise Guide to Pharmacology 2019/20
8392
Concise Guide to Pharmacology 2021/22
8392
Concise Guide to Pharmacology 2023/24
8392
Guide to Pharmacology
8392
External IDs
4
Properties
(calculated by RDKit )
Molecular Weight
264.12
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
4
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
2
cLogP
-0.71
TPSA
117.42
Fraction CSP3
0.5
Chiral centers
4.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Source data