General
Preferred name
d-Borneol
Synonyms
(+)-Borneol ()
DEXBORNEOL ()
borneol ()
(-) Borneol ()
Borneol, d- ()
FEMA NO. 2157, (+)- ()
D-camphanol ()
Borneol d-form ()
P&D ID
PD050664
CAS
464-43-7
Tags
available
drug
natural product
Drug Status
approved
investigational
Max Phase
3.0
Drug indication
Stroke
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
PRICE
29
DESCRIPTION
(+)-BORNEOL (d-Borneol) is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 ??M.
DESCRIPTION
This is the (+) (or dex) enantiomer of borneol, a plant-derived natural product.
(GtoPdb)
DESCRIPTION
(+)-Borneol is a positive allosteric modulator of α1β2γ2L subunit-containing GABAA receptors. (+)-Borneol is a bicyclic monoterpene and a stereoisomer of (–)-borneol that has analgesic, neuroprotective, antioxidant, and antimicrobial activities.
(Enamine Bioactive Compounds)
DESCRIPTION
(+)-BORNEOL (d-Borneol) is a natural bicyclic monoterpene used for analgesia and anesthesia in traditional Chinese medicine; enhances GABA receptor activity with an EC50 of 248 μM.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
6
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
34
Molecular Weight
154.14
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
2
Aromatic Ring Count
0
cLogP
2.19
TPSA
20.23
Fraction CSP3
1.0
Chiral centers
3.0
Largest ring
5.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
GABA
Pathway
Membrane Transporter/Ion Channel
Neuroscience
Source data
