General
Preferred name
rauwolscine
Synonyms
RAUWOLSCINE HYDROCHLORIDE ()
¦Á-Yohimbine hydrochloride ()
Corynanthidine hydrochloride ()
Isoyohimbine hydrochloride ()
??-Yohimbine hydrochloride ()
Isoyohimbine hydrochloride, α-Yohimbine hydrochloride, corynanthidine hydrochloride ()
Isoyohimbine hydrochloride, ??-Yohimbine hydrochloride, corynanthidine hydrochloride ()
[3H]rauwolscine ()
Rauwolscine (hydrochloride) ()
α-Yohimbine hydrochloride ()
Isoyohimbine hydrochloride, ¦Á-Yohimbine hydrochloride, corynanthidine hydrochloride ()
Rauwolscine HCl ()
[3H]rauwolscine ()
Rauwolscine (hydrochloride) ()
P&D ID
PD050456
CAS
6211-32-1
131-03-3
112350-93-3
Tags
drug candidate
natural product
available
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Please note that the structure shown here does not specify the position of the tritiated hydrogen atoms.
(GtoPdb)
DESCRIPTION
alpha2 Adrenoceptor antagonist
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
11
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugMAP
EU-OPENSCREEN Bioactive Compound Library
LOPAC library
Mcule NIBR MoA Box Subset
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
37
Properties
(calculated by RDKit )
Molecular Weight
354.19
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
5
Aromatic Ring Count
2
cLogP
2.65
TPSA
65.56
Fraction CSP3
0.57
Chiral centers
5.0
Largest ring
6.0
QED
0.77
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Selectivity
alpha2
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Target
??2 adrenergic receptor
¦Á2 adrenergic receptor
ADRA2A, ADRA2B, ADRA2C, HTR1B, HTR1D, HTR1E, HTR2B
MOA
Adrenergic Receptor
alpha-Adrenoceptor Antagonists
Adrenergic Receptor antagonist
Member status
member
Source data