General
Preferred name
quinelorane
Synonyms
Quinelorane dihydrochloride ()
QUINELORANE HYDROCHLORIDE ()
Quinelorane (dihydrochloride) ()
LY163502 ()
LY-163502 ()
P&D ID
PD050296
CAS
97548-97-5
97466-90-5
Tags
drug candidate
natural product
available
Drug indication
Antiparkinsonian
Antihypertensive
Male sexual disorder
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
D2 Dopamine receptor agonist; 2-aminopyridine analog of Quinpirole
(LOPAC library)
DESCRIPTION
Selective CCK2 antagonist
(Tocris Bioactive Compound Library)
DESCRIPTION
Quinelorane hydrochloride, 2-aminopyridine analog of quinpirole, is a dopamine D2 and D3 receptor agonist (Ki= 5.7 and 3.4 nM respectively).
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
BOC Sciences Bioactive Compounds
ChEMBL Drugs
Drug Repurposing Hub
DrugMAP
Guide to Pharmacology
LOPAC library
MedChem Express Bioactive Compound Library
ReFrame library
Tocris Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
32
Molecular Weight
246.18
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
3
Aromatic Ring Count
1
cLogP
1.65
TPSA
55.04
Fraction CSP3
0.71
Chiral centers
2.0
Largest ring
6.0
QED
0.86
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
D2
Primary Target
Non-selective Dopamine
MOA
Agonist
Dopamine Receptor agonist
Target
DRD2, DRD3
Dopamine Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Source data
