General
Preferred name
RELENOPRIDE
Synonyms
YKP-GI ()
Relenopride (hydrochloride) ()
RELENOPRIDE HYDROCHLORIDE ()
YKP10811 (hydrochloride) ()
YKP10811 ()
YKP-10811 ()
YKP10811*HCl ()
P&D ID
PD050126
CAS
1221416-43-8
1221416-42-7
Tags
available
drug candidate
Drug indication
Constipation
Drug Status
investigational
Max Phase
Phase 2
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Relenopride (YKP10811) is a partial agonist which is selective for the serotonin 5-HT4 receptor .
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
492.19
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
9
Ring Count
3
Aromatic Ring Count
2
cLogP
3.74
TPSA
119.91
Fraction CSP3
0.42
Chiral centers
1.0
Largest ring
6.0
QED
0.46
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuronal Signaling
Target
5-HT Receptor
Source data
