General
Preferred name
Flortaucipir F-18
Synonyms
FLORTAUCIPIR F 18 ()
flortaucipir (18F) ()
18F-AV-1451 ()
[F-18]T807 ()
T807 F-18 ()
(18f)flortaucipir ()
LY-3191748 ()
AV-1451 F-18 ()
Flortaucipir f18 ()
(F-18)T807 ()
Tauvid ()
T-807 F-18 ()
LY3191748 ()
P&D ID
PD050058
CAS
1522051-90-6
Tags
drug
Approved by
FDA
First approval
2020
Drug Status
approved
investigational
Max Phase
4.0
Drug indication
neurodegenerative disease
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Flortaucipir (18F) is an investigational PET imaging agent (diagnostic radiopharmaceutical) designed to visualise tau protein (MAPT; P10636) in Alzheimer's disease brains. Compare with the approved agent, , used to visualise β-amyloid.
DESCRIPTION Flortaucipir (18F) is an investigational PET imaging agent (diagnostic radiopharmaceutical) designed to visualise tau protein (MAPT; P10636) in Alzheimer's disease brains. Compare with the approved agent, , used to visualise β-amyloid. (GtoPdb)
Compound Sets
7
ChEMBL Approved Drugs
CHEMBL3545253
ChEMBL Drugs
CHEMBL3545253
DrugBank
DB14914
DrugBank Approved Drugs
DB14914
DrugCentral
5396
DrugCentral Approved Drugs
5396
Guide to Pharmacology
9100
External IDs
12
Properties
(calculated by RDKit )
Molecular Weight
262.09
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
4
Aromatic Ring Count
4
cLogP
3.92
TPSA
41.57
Fraction CSP3
0.0
Chiral centers
0.0
Largest ring
6.0
QED
0.53
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Source data