General
Preferred name
ACET
Synonyms
UBP316 ()
P&D ID
PD049867
CAS
936095-50-0
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Positive allosteric modulator of GABAA receptors (Tocris Bioactive Compound Library)
Compound Sets
8
Concise Guide to Pharmacology 2017/18
4123
Concise Guide to Pharmacology 2019/20
4123
Concise Guide to Pharmacology 2021/22
4123
Concise Guide to Pharmacology 2023/24
4123
DrugMAP
DMB2463
Guide to Pharmacology
4123
MedChem Express Bioactive Compound Library
HY-107601
Tocris Bioactive Compound Library
2728
External IDs
14
Properties
(calculated by RDKit )
Molecular Weight
429.1
Hydrogen Bond Acceptors
8
Hydrogen Bond Donors
3
Rotatable Bonds
7
Ring Count
3
Aromatic Ring Count
3
cLogP
1.21
TPSA
144.62
Fraction CSP3
0.2
Chiral centers
1.0
Largest ring
6.0
QED
0.51
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Primary Target
Kainate Receptors
MOA
Antagonist
Pathway
Membrane Transporter/Ion Channel
Neuronal Signaling
Target
iGluR
Source data