General
Preferred name
MK-7725
Synonyms
MK7725 ()
P&D ID
PD049816
CAS
1034152-95-8
Tags
drug candidate
Drug indication
Obesity
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION MK-7725 is reported as a selective non-peptide agonist of the BB3 receptor . (GtoPdb)
DESCRIPTION MK7725 is a potent, selective bombesin receptor subtype-3 agonist. It is used for the treatment of obesity. (BOC Sciences Bioactive Compounds)
Compound Sets
7
BOC Sciences Bioactive Compounds
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMAP
Guide to Pharmacology
External IDs
11
Properties
(calculated by RDKit )
Molecular Weight
615.1
Hydrogen Bond Acceptors
9
Hydrogen Bond Donors
2
Rotatable Bonds
5
Ring Count
5
Aromatic Ring Count
4
cLogP
5.73
TPSA
130.68
Fraction CSP3
0.24
Chiral centers
0.0
Largest ring
7.0
QED
0.27
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Solubility
10 mM in DMSO
Source data