General
Preferred name
S-Apomorphine
Synonyms
(S)APOMORPHINE ()
S(+)-apomorphine ()
P&D ID
PD049796
CAS
39478-62-1
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
investigational
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
S(+)-apomorphine a brain-penetrating activator of the activator of the nuclear erythroid 2-related-factor 2 (Nrf2)-ARE (antioxidant response element) pathway . This compound is a receptor-inactive enantiomer of the clinically approved dopamine-receptor agonist (R(-)-apomorphine).
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
21
Molecular Weight
267.13
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
0
Ring Count
4
Aromatic Ring Count
2
cLogP
2.85
TPSA
43.7
Fraction CSP3
0.29
Chiral centers
1.0
Largest ring
6.0
QED
0.72
QED
0.72
Structural alerts
1
historic compounds (Chemical Probes.org)
Obsolete
Related compounds
Custom attributes
(extracted from source data)
Source data
