General
Preferred name
thymidine
Synonyms
5-Methyldeoxyuridine ()
Deoxyribothymidine ()
DThyd ()
NSC 21548 ()
Thymidin ()
Deoxythymidine ()
1-(2-Deoxy-β-D-threo-pentofuranosyl)thymine ()
Deoxythymidine, 2'-Deoxythymidine, 5-Methyldeoxyuridine, DThyd ()
Thymidine (NSC 21548) ()
DOXRIBTIMINE ()
1-(2-Deoxy-¦Â-D-threo-pentofuranosyl)thymine ()
Doxribtimine component of mt-1621 2'-deoxythymidine ()
NSC-21548 ()
Zidovudine related compound d rs ()
2'deoxythymidine ()
2'-deoxythymidine ()
Thymidinedeoxyriboside ()
MT1621 (dT) ()
Thymine-2-desoxyriboside ()
Zidovudine related compound d ()
Thymidine-d4 ()
P&D ID
PD049699
CAS
35902-13-7
50-88-4
1211376-53-2
146183-25-7
16053-52-4
50-89-5
347841-67-2
Tags
available
drug candidate
Drug indication
Discovery agent
peritoneum cancer
Drug Status
experimental
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
1-(2-Deoxy-¦Â-D-threo-pentofuranosyl)thymine is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
PRICE
29
DESCRIPTION
Thymidine (DThyd) is a cell synchronizing agent and a specific precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis and can cause cell cycle arrest in the G1/S phase.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
4
Compound Sets
16
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugBank
DrugMAP
EU-OPENSCREEN Bioactive Compound Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
45
Molecular Weight
242.09
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
2
Ring Count
2
Aromatic Ring Count
1
cLogP
-1.51
TPSA
104.55
Fraction CSP3
0.6
Chiral centers
3.0
Largest ring
6.0
QED
0.58
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
DNA/RNA Synthesis
Endogenous Metabolite
Nucleoside antimetabolite/analog
Member status
member
MOA
Thymidine kinase 1 ligand
Thymidine kinase 2 ligand
Pathway
Cell Cycle/Checkpoint
DNA Damage/DNA Repair
Metabolism
Cell Cycle/DNA Damage
Source data
