General
Preferred name
NGD 94-1
Synonyms
NGD-94-1 ()
[3H]NGD941 ()
P&D ID
PD049225
CAS
178928-68-2
Tags
available
drug candidate
Drug indication
Schizophrenia
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
NGD 94-1 is a dopamine D4 receptor ligand and it is selective over D1, D2, D3 and D5 receptors.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
11
BOC Sciences Bioactive Compounds
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugMAP
DrugMatrix
Ki Database
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
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External IDs
21
Molecular Weight
320.17
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
4
Ring Count
4
Aromatic Ring Count
3
cLogP
2.19
TPSA
60.94
Fraction CSP3
0.28
Chiral centers
0.0
Largest ring
6.0
QED
0.8
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
DRD4
MOA
Dopamine Receptor antagonist
Source data
