General
Preferred name
JNJ-18038683
Synonyms
P&D ID
PD049050
CAS
851373-91-6
851376-05-1
Tags
available
drug candidate
Drug indication
Major depressive disorder
Drug Status
investigational
Max Phase
Phase 2
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION JNJ-18038683 is a 1:1 mixture of PubChem CID 11151899 and citric acid (2-hydroxypropane-1,2,3-tricarboxylic acid, PubChem CID 311) . We only show the structure for the former moeity which is a selective serotonin 5-HT7 receptor antagonist. (GtoPdb)
Compound Sets
8
ChEMBL Drugs
CHEMBL4205783
CHEMBL4297293
Concise Guide to Pharmacology 2017/18
8432
Concise Guide to Pharmacology 2019/20
8432
Concise Guide to Pharmacology 2021/22
8432
Concise Guide to Pharmacology 2023/24
8432
DrugMAP
DMV1T59
Guide to Pharmacology
8432
MedChem Express Bioactive Compound Library
HY-19889
External IDs
20
Properties
(calculated by RDKit )
Molecular Weight
337.13
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
3
cLogP
3.94
TPSA
29.85
Fraction CSP3
0.25
Chiral centers
0.0
Largest ring
7.0
QED
0.78
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuronal Signaling
Target
5-HT Receptor
Source data