General
Preferred name
PD048981
Synonyms
3-hydroxylauric acid ()
3-Hydroxydodecanoic acid ()
3-hydroxy Lauric Acid ()
P&D ID
PD048981
CAS
1883-13-2
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
3-Hydroxydodecanoic acid is a medium-chain fatty acid. 3-Hydroxydodecanoic acid activates GPR84 and promotes IL-12 production. 3-Hydroxydodecanoic acid has anticancer activity against colon cancer, lung cancer, and melanoma[1][2].
DESCRIPTION
3-Hydroxy lauric acid is a hydroxylated fatty acid that is found in bacteria as well as Pseudosuberites and D. calyx sea sponges. It has antifungal activity against a panel of seven fungi (MICs = 10-50 μg/ml). 3-Hydroxy lauric acid acts as a partial agonist of GPR84 receptors in vitro (EC50 = 5.24 μM).
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
23
Molecular Weight
216.17
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
10
Ring Count
0
Aromatic Ring Count
0
cLogP
2.96
TPSA
57.53
Fraction CSP3
0.92
Chiral centers
1.0
Largest ring
0.0
QED
0.55
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Metabolic Enzyme/Protease
Target
Endogenous Metabolite
Source data
