General
Preferred name
MT-II
Synonyms
MELANOTAN II ()
Melanotan (MT)-II ()
MELATONAN ()
Melanotan II (acetate) ()
P&D ID
PD048907
CAS
121062-08-6
Tags
available
drug candidate
Drug indication
Female sexual arousal dysfunction
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Melanotan (MT)-II, a synthetic melanocortin receptor agonist, is an analogue of the peptide hormone α-melanocyte-stimulating hormone (α-MSH).
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
0
Organisms
1
Compound Sets
10
Cayman Chemical Bioactives
Drug Repurposing Hub
DrugMAP
EUbOPEN Chemogenomics Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
31
Molecular Weight
1023.54
Hydrogen Bond Acceptors
11
Hydrogen Bond Donors
13
Rotatable Bonds
17
Ring Count
5
Aromatic Ring Count
4
cLogP
-1.25
TPSA
384.76
Fraction CSP3
0.46
Chiral centers
7.0
Largest ring
23.0
QED
0.03
QED
0.03
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
melanocortin receptors
Melanocortin Receptor
5-alpha Reductase
Member status
member
MOA
MC1R agonist
MC3R agonist
MC4R agonist
MC5R agonist
melanocortin receptor agonist
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Recommended Cell Concentration
None
Source data
