General
Preferred name
Pregnenolone monosulfate
Synonyms
Pregn-5-en-20-on-3¦Â-yl sulfuric acid ()
Pregnenolone sulfate sodium salt ()
Pregn-5-en-20-on-3??yl sulfuric acid ()
3¦Â-Hydroxy-5-pregnen-20-one monosulfate ()
3¦Â-Hydroxy-5-pregnen-20-one monosulfate (sodium salt) ()
Pregnenolone monosulfate (sodium) ()
3β-Hydroxy-5-pregnen-20-one monosulfate (sodium) ()
3β-Hydroxy-5-pregnen-20-one monosulfate ()
PREGNENOLONE SULFATE SODIUM ()
[3H]pregnenolone sulphate ()
Pregnenolone sulfate (sodium salt) ()
P&D ID
PD048239
CAS
1852-38-6
1247-64-9
Tags
natural product
available
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
The position of the radiolabelled hydrogen atom in this compound is unspecified.
(GtoPdb)
DESCRIPTION
Selective Kir3.1/3.2 (GIRK1/2) channel activator
(Tocris Bioactive Compound Library)
DESCRIPTION
Pregnenolone sulfate, a metabolite of the natural steroid hormone pregnenolone, is a neurosteroid that has been demonstrated to antagonize the GABAA receptor chloride channel.
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
10
BOC Sciences Bioactive Compounds
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Tocris Bioactive Compound Library
ZINC Tool Compounds
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
34
Molecular Weight
396.2
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
4
Aromatic Ring Count
0
cLogP
4.34
TPSA
80.67
Fraction CSP3
0.86
Chiral centers
7.0
Largest ring
6.0
QED
0.57
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Primary Target
NMDA Receptors
MOA
Modulator
Pathway
Autophagy
GPCR/G protein
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Neuronal Signaling
Target
Cannabinoid Receptor
Endogenous Metabolite
TRP Channel
Source data
