General
Preferred name
PMID24946214C3b
Synonyms
compound 3b [PMID: 24946214] ()
P&D ID
PD048190
Tags
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Compound 3b is reported to inhibit the chymotrypsin-like (ChT-L) and post-glutamyl peptide hydrolyzing (PGHP) activities of the 20S proteasome . (GtoPdb)
Cell lines
41
Organisms
0
Compound Sets
2
DrugMAP
DMNPA2C
Guide to Pharmacology
8618
External IDs
7
Properties
(calculated by RDKit )
Molecular Weight
330.18
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
3
Rotatable Bonds
7
Ring Count
2
Aromatic Ring Count
2
cLogP
0.93
TPSA
91.56
Fraction CSP3
0.41
Chiral centers
1.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Source data