General
Preferred name
SU-14813
Synonyms
P&D ID
PD047974
Tags
drug candidate
Drug indication
Breast cancer
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION SU-14813 is an oral, multitargeted receptor tyrosine kinase inhibitor targeting VEGFRs, PDGFRs, KIT, and FLT3 . (GtoPdb)
Compound Sets
6
Concise Guide to Pharmacology 2017/18
5712
Concise Guide to Pharmacology 2019/20
5712
Concise Guide to Pharmacology 2021/22
5712
Concise Guide to Pharmacology 2023/24
5712
DrugMAP
DMNRW68
Guide to Pharmacology
5712
External IDs
4
Properties
(calculated by RDKit )
Molecular Weight
442.2
Hydrogen Bond Acceptors
6
Hydrogen Bond Donors
3
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
1
cLogP
1.34
TPSA
103.26
Fraction CSP3
0.43
Chiral centers
2.0
Largest ring
6.0
QED
0.58
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Therapeutic Class
Anticancer Agents
Source data