General
Preferred name
TRANYLCYPROMINE
Synonyms
Parstelin ()
Pamate ()
Tranylcypromine hydrochloride ()
Tranylcypromine,(+) ()
Tranylcypromine,(-) ()
Tranylcypromine HCl ()
Tranylcypromine ()
P&D ID
PD047971
CAS
61-81-4
3548-91-2
1986-47-6
Tags
covalent binder
natural product
drug
available
Drug Status
investigational
approved
withdrawn
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
The approved drug tranylcypromine is a racemic mixture of two enantiomers. The structure shown here does not specify stereochemistry and represents the mixture. The two enantiomers are represented by CID 19493</> and CID 26070.
(GtoPdb)
DESCRIPTION
MAO inhibitor; antidepressant
(LOPAC library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
1
Organisms
1
Compound Sets
17
AdooQ Bioactive Compound Library
CeMM library of unique drugs (CLOUD)
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
CovalentInDB
DrugBank
DrugBank Approved Drugs
DrugMatrix
Guide to Pharmacology
Ki Database
LOPAC library
LSP-MoA library (Laboratory of Systems Pharmacology)
Other bioactive compounds
ReFrame library
Withdrawn 2.0
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
38
Molecular Weight
133.09
Hydrogen Bond Acceptors
1
Hydrogen Bond Donors
1
Rotatable Bonds
1
Ring Count
2
Aromatic Ring Count
1
cLogP
1.5
TPSA
26.02
Fraction CSP3
0.33
Chiral centers
2.0
Largest ring
6.0
QED
0.62
Structural alerts
1
historic compounds (Chemical Probes.org)
Obsolete
Related compounds
Custom attributes
(extracted from source data)
Selectivity
MAO
MOA
monoamine oxidase inhibitor
Target
Monoamine Oxidase
ATC
N06AF04
Toxicity type
cardiovascular
Source data
