General
Preferred name
HT-2157
Synonyms
SNAP-37889 ()
HT2157 ()
SNAP37889 ()
SNAP 37889 ()
P&D ID
PD047842
CAS
303149-14-6
303149-14-8
1000273-85-7
Tags
available
drug candidate
Drug indication
Cognitive impairment
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
This compound is represented on ChEMBL by the entry CHEMBL210288 which specified stereochemistry around the double bond.
(GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
9
Cayman Chemical Bioactives
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
DrugMAP
Guide to Pharmacology
Novartis Chemogenetic Library (NIBR MoA Box)
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
10
Molecular Weight
366.1
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
0
Rotatable Bonds
2
Ring Count
4
Aromatic Ring Count
3
cLogP
5.5
TPSA
32.67
Fraction CSP3
0.05
Chiral centers
0.0
Largest ring
6.0
QED
0.59
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuroscience
Target
galanin-3 receptor (Gal3)
Galanin-3 (GAL3)
Member status
virtual
MOA
Galanin GAL3 Antagonists
Signal Transduction Modulators
Source data
