General
Preferred name
RF9
Synonyms
RF9 (hydrochloride) ()
RF9 acetate ()
P&D ID
PD047838
CAS
876310-60-0
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Modified RFamide
(GtoPdb)
DESCRIPTION
RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist, with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively[1][2].
PRICE
199
DESCRIPTION
RF9 acetate is an effective and selective antagonist of Neuropeptide FF receptor with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
Cayman Chemical Bioactives
DrugMAP
EUbOPEN Chemogenomics Library
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
19
Molecular Weight
482.3
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
6
Rotatable Bonds
11
Ring Count
5
Aromatic Ring Count
1
cLogP
1.16
TPSA
163.19
Fraction CSP3
0.62
Chiral centers
2.0
Largest ring
6.0
QED
0.16
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Member status
member
MOA
Neuropeptide FF Receptor Antagonists
Target
Neuropeptide Y Receptor
NPFF1
NPFF2
Recommended Cell Concentration
None
Source data
