General
Preferred name
PD047827
Synonyms
17alpha-hydroxypregnenolone ()
17a-Hydroxypregnenolone ()
17α-hydroxypregnenolone ()
17?-hydroxy Pregnenolone ()
P&D ID
PD047827
CAS
387-79-1
Tags
available
drug candidate
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION 17a-Hydroxypregnenolone is an intermediate in the synthesis of steroid hormones and may be related to the synthesis of sex hormones or adrenal hormones. The sulfate form of 17a-Hydroxypregnenolone (17¦Á-hydroxypregnenolone sulfate) is the main interfering substance in neonatal plasma, which can significantly affect the immunoassay results of 17¦Á-hydroxyprogesterone (17-OHP) by cross-reacting with antibodies[1].
PRICE 29
DESCRIPTION 17a-Hydroxypregnenolone, a pregnane steroid, is a prohormone involved in the synthesis of dehydroepiandrosterone (DHEA). (TargetMol Bioactive Compound Library)
Compound Sets
5
Cayman Chemical Bioactives
29181
DrugMAP
DMT2EPG
Guide to Pharmacology
5103
MedChem Express Bioactive Compound Library
HY-113263
TargetMol Bioactive Compound Library
T10048
External IDs
42
Properties
(calculated by RDKit )
Molecular Weight
332.24
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
2
Rotatable Bonds
1
Ring Count
4
Aromatic Ring Count
0
cLogP
3.63
TPSA
57.53
Fraction CSP3
0.86
Chiral centers
7.0
Largest ring
6.0
QED
0.72
Structural alerts
2
aggregator (Aggregator Advisor)
Aggregators
aggregator (ZINC)
Aggregators
Custom attributes
(extracted from source data)
Target
Endogenous Metabolite
Human Endogenous Metabolite
Pathway
Metabolic Enzyme/Protease
Metabolism
Source data