General
Preferred name
ZK-93423
Synonyms
ZK 93423 ()
ZK 93423 hydrochloride ()
ZK93423 ()
P&D ID
PD047817
CAS
83910-44-5
Tags
available
drug candidate
Drug indication
Epileptic seizures
Drug Status
investigational
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION Potent benzodiazepine agonist (Tocriscreen Plus)
DESCRIPTION Potent benzodiazepine agonist (Tocriscreen Total)
Cell lines
0
Organisms
1
Compound Sets
11
Drug Repurposing Hub
DrugBank
DB17063
DrugMAP
DMFWMKZ
Guide to Pharmacology
4346
JUMP-Target 1 Compound Set
121926
Ki Database
ZK 93423
Mcule NIBR MoA Box Subset
MCULE-4275785851
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
Tocriscreen Plus
1994
Tocriscreen Total
External IDs
22
Properties
(calculated by RDKit )
Molecular Weight
390.16
Hydrogen Bond Acceptors
5
Hydrogen Bond Donors
1
Rotatable Bonds
7
Ring Count
4
Aromatic Ring Count
4
cLogP
4.62
TPSA
73.44
Fraction CSP3
0.22
Chiral centers
0.0
Largest ring
6.0
QED
0.47
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target Type
Ion Channels
Member status
member
MOA
Anxiolytics
benzodiazepine receptor agonist
Target
GABRA1, GABRA2, GABRA3, GABRA5, GABRB2, GABRG2
GABRB2
Source data