General
Preferred name
SARCOSINE
Synonyms
N-Methylaminoacetic acid ()
Sarcosin ()
Sarcosinic acid ()
Methylglycine ()
N-methylglycine ()
Methylaminoacetic acid ()
N-methylglycine, Sarcosinic acid, Methylaminoacetic acid, Methylglycine ()
Methylamino-Acetic Acid ()
P&D ID
PD047812
CAS
107-97-1
68411-97-2
25951-24-0
Tags
available
drug candidate
Drug indication
Discovery agent
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
15
Cayman Chemical Bioactives
ChEMBL Drugs
Concise Guide to Pharmacology 2017/18
Concise Guide to Pharmacology 2019/20
Concise Guide to Pharmacology 2021/22
Concise Guide to Pharmacology 2023/24
Drug Repurposing Hub
DrugBank
DrugMAP
Enamine BioReference Compounds
Guide to Pharmacology
MedChem Express Bioactive Compound Library
ReFrame library
Selleckchem Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
46
Properties
(calculated by RDKit )
Molecular Weight
89.05
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
2
Rotatable Bonds
2
Ring Count
0
Aromatic Ring Count
0
cLogP
-0.71
TPSA
49.33
Fraction CSP3
0.67
Chiral centers
0.0
Largest ring
0.0
QED
0.47
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
Neuronal Signaling
Membrane Transporter/Ion Channel
Metabolic Enzyme/Protease
Target
GlyT1
N-methyl-D-aspartate receptor
SLC6A9
Endogenous Metabolite
GlyT
Amino acid transporter,GlyT,NMDAR
MOA
GlyT inhibitor
NMDAR inhibitor
glycine transporter inhibitor
Source data
