General
Preferred name
APICIDIN
Synonyms
Acipidin ()
P&D ID
PD047774
CAS
183506-66-3
Tags
obsolete probe
drug candidate
natural product
available
Drug indication
Solid tumour/cancer
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Acipidin is a natural product fungal metabolite . It inhibits cancer cell proliferation , via histone deacetylase (HDAC) inhibition.
The compound has broad-spectrum activity against apicomplexan parasites including Plasmodium species . The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. (GtoPdb)
The compound has broad-spectrum activity against apicomplexan parasites including Plasmodium species . The Malaria tab on this ligand page provides additional curator comments of relevance to the Guide to MALARIA PHARMACOLOGY. (GtoPdb)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Cell lines
7
Organisms
3
Compound Sets
6
DrugMAP
Guide to Pharmacology
Mcule NIBR MoA Box Subset
Novartis Chemogenetic Library (NIBR MoA Box)
Obsolete Compounds
Reference compounds for characterizing cellular injury in high-content cellular morphology assays
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
18
Molecular Weight
623.37
Hydrogen Bond Acceptors
7
Hydrogen Bond Donors
3
Rotatable Bonds
12
Ring Count
4
Aromatic Ring Count
2
cLogP
3.07
TPSA
138.84
Fraction CSP3
0.62
Chiral centers
5.0
Largest ring
12.0
QED
0.31
Structural alerts
1
historic compounds (Chemical Probes.org)
Obsolete
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
HDAC inhibitor
Cellular injury category
HDAC
Source data
