General
Preferred name
PB-28
Synonyms
PB 28 dihydrochloride ()
PB28 ()
PB28 (dihydrochloride) ()
PB 28 (hydrochloride) ()
P&D ID
PD047597
CAS
172906-90-0
172907-03-8
Tags
available
drug candidate
Drug indication
Coronavirus Disease 2019 (COVID-19)
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Cell lines
4
Organisms
2
Compound Sets
7
Axon Medchem Screening Library
1272
Cayman Chemical Bioactives
31742
DrugMAP
DMMNQ1B
DMSXZ19
Guide to Pharmacology
6681
MedChem Express Bioactive Compound Library
HY-108511
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
External IDs
21
Properties
(calculated by RDKit )
Molecular Weight
370.3
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
0
Rotatable Bonds
6
Ring Count
4
Aromatic Ring Count
1
cLogP
4.85
TPSA
15.71
Fraction CSP3
0.75
Chiral centers
1.0
Largest ring
6.0
QED
0.71
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
member
Target
Sigma-2 agonist
SARS-CoV
Sigma Receptor
Therapeutic Class
Antiviral Agents
Pathway
Anti-infection
Apoptosis
Neuronal Signaling
Source data