General
Preferred name
FLUPAROXAN
Synonyms
GR50360 ()
FLUPAROXAN HYDROCHLORIDE ()
(3as,9as)-fluparoxan ()
Fluparoxan, (-)- ()
(-)-fluparoxan ()
GR50360A, (-)- ()
GR50360A ()
GR-50360A, (-)- ()
P&D ID
PD047531
CAS
105182-45-4
105227-44-9
Tags
available
drug candidate
Drug indication
Depression
Drug Status
investigational
Max Phase
2.0
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
Fluparoxan is an orally active, selective and competitive alpha 2-adrenoceptor antagonist. Fluparoxan is an anti-depressant agent[1][2].
PRICE
408
DESCRIPTION
Fluparoxan hydrochloride is a highly selective and potent ??2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmental disorders and neurodegenerative diseases.
DESCRIPTION
Fluparoxan hydrochloride is a highly selective and potent α2-adrenoceptor antagonist for the prevention, amelioration or treatment of neurodevelopmental disorders and neurodegenerative diseases.
(TargetMol Bioactive Compound Library)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
5
ChEMBL Drugs
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
TargetMol Bioactive Compound Library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
33
Molecular Weight
195.07
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
0
Ring Count
3
Aromatic Ring Count
1
cLogP
0.94
TPSA
30.49
Fraction CSP3
0.4
Chiral centers
2.0
Largest ring
6.0
QED
0.67
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Target
α2-adrenoceptor
Adrenergic Receptor
Pathway
GPCR/G protein
Neuroscience
Neuronal Signaling
Source data
