General
Preferred name
WAY 100135
Synonyms
WAY 100135 dihydrochloride ()
WAY-100135 (dihydrochloride) ()
WAY-100135 ()
P&D ID
PD047231
CAS
133025-23-7
149055-79-8
Tags
available
drug candidate
Drug indication
Discovery agent
Probe control
Probe control not defined
Orthogonal probes
0
No orthogonal probes found
Similar probes
0
No structurally similar probes found
Structure
P&D probe-likeness score
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION
WAY 100135 dihydrochloride is a selective 5-HT1A antagonist (IC50 = 15 nM).
(BOC Sciences Bioactive Compounds)
[[ p.pathway_name ]]
[[ compound.targets[tid].gene_name ]]
Compound Sets
7
Axon Medchem Screening Library
BOC Sciences Bioactive Compounds
DrugMAP
Guide to Pharmacology
MedChem Express Bioactive Compound Library
Novartis Chemogenetic Library (NIBR MoA Box)
ReFrame library
[[ a.name ]]
[[ ligand_id ]]
free of charge
External IDs
22
Molecular Weight
395.26
Hydrogen Bond Acceptors
4
Hydrogen Bond Donors
1
Rotatable Bonds
6
Ring Count
3
Aromatic Ring Count
2
cLogP
3.52
TPSA
44.81
Fraction CSP3
0.46
Chiral centers
1.0
Largest ring
6.0
QED
0.81
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Member status
virtual
MOA
5-HT1A Receptor Antagonists
ADRA1B gene modulator
Target
5-HT1A antagonist
5-HT Receptor
Pathway
GPCR/G protein
Neuronal Signaling
Source data
