General
Preferred name
LEUPROLIDE
Synonyms
Leuprorelin Acetate ()
leuprorelin ()
LEUPROLIDE ACETATE ()
Enantone ()
leuprorelin acetate, Camurus ()
LEUPROLIDE MESYLATE ()
TAP-144 FREE BASE ()
NSC-377526 ()
Leuprorelin slow release ()
CKD-841 ()
Leuporelin ()
ABBOTT-43818 FREE BASE ()
(-)-leuprolide ()
Lutrate depot ()
Lupron Depot Ped ()
Lucrin ()
Lupron Depot-Ped ()
Leuprolide monoacetate ()
TAP-144 ()
Leuplin ()
Lutrate depot kit ()
Lupaneta ()
Leuprorelin acetate ()
ABBOTT-43818 ()
Lupron depot-ped kit ()
Fensolvi kit ()
Fensolvi ()
Lupron ()
Leuporelin acetate ()
Viadur ()
Carcinil ()
Prostap ()
Tap-144-sr ()
Trenantone ()
Eligard ()
Lupron Depot ()
Eligard kit ()
A-43818 ()
Leuprorelin mesilate ()
Camcevi kit ()
Leuprorelin mesylate ()
Camcevi ()
Leuprorelin (acetate) ()
P&D ID
PD047224
CAS
74381-53-6
53714-56-0
Tags
available
drug
Approved by
EMA
FDA
First approval
2021
1985
Drug Status
investigational
approved
Drug indication
Antineoplastic
Prostate cancer
LHRH Agonist
Max Phase
Phase 4
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION The marketed formulation contains leuprolide acetate. (GtoPdb)
Compound Sets
16
Cayman Chemical Bioactives
22275
ChEMBL Approved Drugs
CHEMBL1201199
CHEMBL1200775
CHEMBL4802223
ChEMBL Drugs
CHEMBL1201199
CHEMBL1200775
CHEMBL4802223
Drug Repurposing Hub
DrugBank
DB00007
DrugBank Approved Drugs
DB00007
DrugCentral
1559
DrugCentral Approved Drugs
1559
DrugMAP
DM5XPIJ
DM15HAT
DrugMAP Approved Drugs
DM5XPIJ
DM15HAT
Guide to Pharmacology
1175
LSP-MoA library (Laboratory of Systems Pharmacology)
CHEMBL1201199
Natural product-based probes and drugs
NCATS Inxight Approved Drugs
EFY6W0M8TG
ReFrame library
TargetMol Bioactive Compound Library
T5018
T5021
External IDs
81
Properties
(calculated by RDKit )
Molecular Weight
1208.65
Hydrogen Bond Acceptors
14
Hydrogen Bond Donors
16
Rotatable Bonds
32
Ring Count
6
Aromatic Ring Count
4
cLogP
-1.23
TPSA
429.04
Fraction CSP3
0.53
Chiral centers
9.0
Largest ring
6.0
QED
0.02
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Pathway
GPCR/G protein
Target
GNRHR
MOA
GNRH Receptor
gonadotropin releasing factor hormone receptor agonist
Indication
prostate cancer
Biosynthetic Origin
Peptide (Ribosomal)
Therapeutic Indication
Hormone
Therapeutic Class
Hormone Therapy
Anticancer Agents
Source data