General
Preferred name
VPC171
Synonyms
VCP 171 ()
VCP171 ()
P&D ID
PD047176
CAS
1018830-99-3
Tags
available
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION VPC171 is a positive allosteric modulator (PAM) of the adenosine A1 receptor (A1R). It is compound 9a in Aurelio et al. (2009) . PAMs of the A1R are being investigated as a novel treatment approach for neuropathic pain . (GtoPdb)
DESCRIPTION Highly potent GPR183 (EBI2) agonist (Tocris Bioactive Compound Library)
Compound Sets
3
Cayman Chemical Bioactives
30309
Guide to Pharmacology
8895
Tocris Bioactive Compound Library
6261
External IDs
11
Properties
(calculated by RDKit )
Molecular Weight
347.06
Hydrogen Bond Acceptors
3
Hydrogen Bond Donors
1
Rotatable Bonds
3
Ring Count
3
Aromatic Ring Count
3
cLogP
5.25
TPSA
43.09
Fraction CSP3
0.06
Chiral centers
0.0
Largest ring
6.0
QED
0.66
Structural alerts
0
No structural alerts detected
Custom attributes
(extracted from source data)
Primary Target
Adenosine A1 Receptors
MOA
Modulator
Source data