General
Preferred name
Mipomersen
Synonyms
P&D ID
PD047096
CAS
1000120-98-8
Tags
drug
Drug indication
Familial hypercholesterolemia
Drug Status
approved
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION MOE in the nucleotide image denotes nucleosides with 2'-O-(2-methoxyethyl) modification. The drug formulation contains the sodium salt, mipomersen sodium (CHEMBL2107849). (GtoPdb)
Compound Sets
3
DrugMAP
DMGSRN1
DrugMAP Approved Drugs
DMGSRN1
Guide to Pharmacology
7364
External IDs
3
Properties
(calculated by RDKit )
Molecular Weight
7152.95
Hydrogen Bond Acceptors
199
Hydrogen Bond Donors
26
Rotatable Bonds
156
Ring Count
46
Aromatic Ring Count
26
cLogP
-7.02
TPSA
2667.59
Fraction CSP3
0.63
Chiral centers
89.0
Largest ring
6.0
QED
0.01
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Therapeutic Class
Antisense
Source data