General
Preferred name
muscarine
Synonyms
(±)-Muscarine chloride ()
(+)-Muscarine iodide ()
Muscarine (iodide) ()
(+)-Muscarine (iodide) ()
MUSCARINE CHLORIDE ()
L-(+)-muscarine ()
(+)-Muscarine (tosylate) ()
P&D ID
PD046961
CAS
24570-49-8
2303-35-7
2936-25-6
300-54-9
2209-02-1
82083-43-0
Tags
available
drug candidate
natural product
Drug indication
Discovery agent
Structure
Probe scores
P&D probe-likeness score
[[ v.score ]]%
Structure formats
[[ format ]]
[[ compound[format === 'MOL' ? 'molblock' : format.toLowerCase()] ]]
Description
(extracted from source data)
DESCRIPTION muscarine is a poison found in Inocybe and Clitocybe mushrooms. (GtoPdb)
DESCRIPTION Muscarinic acetylcholine receptor agonist (LOPAC library)
DESCRIPTION High affinity 5-HT2B antagonist; orally active (Tocris Bioactive Compound Library)
DESCRIPTION (+)-Muscarine iodide is a muscarinic receptor agonist with activity similar to that of acetylcholine, involved in the production of gastric acid. (BOC Sciences Bioactive Compounds)
Cell lines
0
Organisms
2
Compound Sets
11
BOC Sciences Bioactive Compounds
muscarine-iodide-cas-24570-49-8-item-121130
Cayman Chemical Bioactives
38853
Concise Guide to Pharmacology 2017/18
3996
Concise Guide to Pharmacology 2019/20
3996
Concise Guide to Pharmacology 2021/22
3996
Concise Guide to Pharmacology 2023/24
3996
DrugMAP
DMNDUJ5
Guide to Pharmacology
3996
LOPAC library
MedChem Express Bioactive Compound Library
HY-107654
Tocris Bioactive Compound Library
3074
External IDs
52
Properties
(calculated by RDKit )
Molecular Weight
174.15
Hydrogen Bond Acceptors
2
Hydrogen Bond Donors
1
Rotatable Bonds
2
Ring Count
1
Aromatic Ring Count
0
cLogP
0.23
TPSA
29.46
Fraction CSP3
1.0
Chiral centers
3.0
Largest ring
5.0
QED
0.61
Structural alerts
0
No structural alerts detected
Related compounds
Custom attributes
(extracted from source data)
Selectivity
Muscarinic
Primary Target
Non-selective Muscarinics
MOA
Agonist
Target
mAChR
Pathway
GPCR/G protein
Neuronal Signaling
Source data